Doctors in the US are screening potential donors of vaginal fluid as they work towards transplants to help women who suffer from bacterial vaginosis (BV). The transplant would mean an option besides antibiotics for women who repeatedly suffer with the infection.
The research is being conducted after the successful testing of 20 women, which allowed doctors to gain insight into the ideal vaginal fluid donor. Now, after approval from the Food and Drugs Administration (FDA), they hope to find more volunteers to screen and to start offering women with BV the transplants.
With their findings reported in the Frontiers in Cellular and Infection Microbiology, it is one of very few studies into the microbiology of the vagina. According to the BBC, doctors at the Johns Hopkins University team were inspired by the success of faecal transplants, which are used to help restore the balance of bacteria in a person’s gut – a much more thoroughly researched are of microbiology.
Similarly to those transplants, a vaginal fluid transplant would involve putting another person’s vaginal fluid inside a patient's vagina with the hope it would restore the natural PH of the vagina.
Bacterial vaginosis occurs when there is a change in the natural balance of bacteria in the vagina, and can occur from having sex, douching, using vaginal wash or hormonal changes as part of the menstrual cycle. One in three women will experience it in their life, but many are unlikely to know what it is as the symptoms can be confused with thrush or a sexually transmitted infection (which it is not classed as).
According to doctors, vaginal fluid with more of a bacterium called lactobacillus crispatus tend to have a lower PH and higher protective lactic acid, both of which can be beneficial to women. Should this be transplanted into women who suffer with BV, it could help treat reoccurrence of the infection.
The donations are collected via a flexible plastic disc that is self-inserted into the vagina and has been compared to a menstrual cup, then transferred into the recipient with a tampon-like applicator.
‘If we can get funding, we could start right away. Some of the donors that we studied said they would want to take part,’ said Dr. Laura Ensign, one of the researchers on the team. ‘We'd plan to give transplants to 40 recipients to begin with. Some would receive the real thing and others a placebo. All of them would get antibiotics for their BV too though.’
Should the screenings prove successful and women were able to receive vaginal fluid transplants, there would likely be more interest by UK doctors. So if you’re a frequent BV sufferer, help might be on the way...
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